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Chemically cleared neurons
A sub-region of the mouse brain that was chemically cleared and imaged with a custom light-sheet microscope. ~25 sub-volumes assembled to form the 3D stack that is presented here.
Action potentials imaged volumetrically at 14 Hz.
Filopodia in a retinal pigment epithelial cell.
Vimentin in an epithelial wound healing response.
Migrating MDA-MB-231 cell volumetrically imaged for 1500 timepoints.
PI3K activity in melanoma membrane ruffles.
Epithelial migration through a three-dimensional extracellular matrix.
Cell-mediated collagen reorganization.
RhoA activity at the cleavage furrow in 3D measured with FRET.
Morphological differences in high-RAS activity cancer cell populations.
Actin speckle microscopy in 3D collagenous environments.
Actin cytoskeletal dynamics in osteosarcoma cells.
Clathrin-mediated endocytosis volumetrically imaged at 3.5 Hz.
Simultaneous imaging of clathrin-mediated endocytosis and intracellular trafficking.
Simultaneous imaging of clathrin-mediated endocytosis and actin.
Human bronchial epithelial cancer cells.
Clathrin-mediated endocytosis in an epithelial sheet.
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